Original
Article
SEROPOSITIVITY
OF SYPHILIS OF THE PATIENTS VISITING GYNAECOLOGY, STI AND DERMATOLOGY CLINIC OF
SULAV HOSPITAL, BELBARI, MORANG
Chaudhary
DK, 1 Shah PK, 1 Khanal H 2
1Department
of Microbiology, St. Xavier’s College, Maitighar, Kathmandu, 2Sulav
Hospital, Belbari, Morang
ABSTRACT
Introduction: Syphilis is a sexually transmitted
disease caused by T. pallidum subspecies
Pallidum. The disease is divided into primary, secondary, and tertiary
stages. Latent syphilis is the stage in which the infection performs a
disappearing act of sorts.
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Objective:
The main purpose of the study is to find out asymptomatic
seroprevalence of syphilis from the blood samples.
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Methods: This Cross-sectional study was
carried out in pathological lab of Sulav Hospital , Belbari, Morang between
May 2011- October 2011. A total of 2139 blood samples of age 16-50 years
patients were enrolled. Sera were screened by rapid plasma reagin (RPR) test
kit. RPR reactive samples only were further tested by T. pallidum
haemagglutination (TPHA) test kit.
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Results:
From the study, overall syphilis seropositivity was 0.51%. The highest
seropositivity of 0.74% (P-value 0.776) was found in age group 31-35 years
with female predominant. Married & previous pregnant population had the
highest seroprevalent of 1.21 (p-value 0.001) and 0.90% (p-value 0.266)
respectively. Mongolian, Ethnic group, Secondary level literate population,
abroad job seekers & returners population and patient with STIs history
had the highest seroprevalent of 0.76% (p-value 0.52), 0.57% (p-value 0.977),
0.86% (p-value 0.728%) and 5.2% (p-value 0.001) respectively.
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Conclusions: Study of seroprevalence of syphilis
in asymptomatic cases is very important which help in the control of its
consequence and prevent the further progression of syphilis.
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Key
words: Asymptomatic, Latent stage, Rapid plasma reagin,
Screening, Syphilis.
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